1265221-96-2

Upstream product

• 1265221-92-8 ethyl 4-(6-chloro-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 1516608-60-8 9-(methoxymethyl)-2-(trimethylsilyl)-9H-purine 
• 6504-64-9 6-chloro-9-(methoxymethyl)-9H-purine 

Downstream Products

• 1265222-03-4 ethyl 4-(9-(methoxymethyl)-6-(thiophen-2-yl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 1265221-97-3 ethyl 4-(6-iodo-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 1265222-05-6 ethyl 4-(6-(4-chlorophenyl)-2-iodo-9-(methoxymethyl)-9H-purin-8-yl)benzoate 
• 1265222-10-3 ethyl 4-(6-(4-chlorophenyl)-9-(methoxymethyl)-2-(4-methoxyphenyl)-9Hpurin-8-yl)benzoate 
• 1265222-02-3 ethyl 4-(6-(4-chlorophenyl)-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 1265222-04-5 ethyl 4-(6-(3-(N-allyl-4-methylphenylsulfonamido)prop-1-yn-1-yl)-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 1265222-01-2 ethyl 4-(6-(3-(dibutylamino)phenyl)-9-(methoxymethyl)-2-(trimethylsilyl)-9H-purin-8-yl)benzoate 
• 1265221-98-4 ethyl 4-(6-(2-(ethoxycarbonyl)allyl)-9-(methoxymethyl)-2-(trimethylsilyl)-9Hpurin-8-yl)benzoate 

Relevant academic research and scientific papers

Regioselective functionalization of purine derivatives at positions 8 and 6 using hindered TMP-amide bases of Zn and Mg

A broad range of purine derivatives were efficiently metalated at positions 8 and 6 using TMP-amide bases. This provided polysubstituted purines in good to very good yields after subsequent trapping of the zinc or magnesium intermediates with various elec

Trifunctionalization of the purine scaffold using Mg and Zn organometallic intermediates

Starting from an appropriate 6-chloro-2-TMS-purine derivative, a regioselective functionalization of the purine scaffold was achieved successively at positions 8, 6, and 2 via zinc and magnesium intermediates which were generated either by a direct zincat