126523-60-2

Upstream product

• 126523-58-8 1-Benzyl-6-(2-hydroxyundecyl)-2-methylpiperidine 
• 106130-14-7 2-methyl-2,3,4,5-tetrahydropyridine 1-oxide 
• 126523-55-5 5-Dioxan-2-yl-pent-2-ylhydroxylamine 
• 106130-15-8 r-3aH-c-7-Methyl-c-2-nonylperhydroisoxazolo<2,3-a>pyridine 
• 126523-54-4 5-Dioxan-2-ylpentan-2-one Oxime 
• 126523-53-3 (2R,3aR,7S)-8-Benzyl-7-methyl-2-nonyl-hexahydro-isoxazolo[2,3-a]pyridin-8-ium; bromide 

Relevant academic research and scientific papers

Synthesis of trans-2,6-Dialkylpiperidines by Intramolecular Amidomercuriation and by 1,3-Cycloaddition of Alkenes to 2-Methyl-2,3,4,5-tetrahydropyridine Oxide

Intramolecular amidomercuriation of methyl N-hept-6-en-2-ylcarbamate and reaction of the resulting organomercurial with sodium borohydride in the presence of acrylonitrile or dec-1-en-3-one has been used to prepare trans-2,6-dialkylpiperidines.A more stereoselective route lies in the cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides followed by reductive cleavage of the resulting perhydroisoxazolopyridine.Both procedures are illustrated by synthesis of the fire ant-venom alkaloid, solenopsin A.