1265313-06-1

Usage

Type of compound

Indole
Indoles are heterocyclic compounds containing a benzene ring fused to a pyrrole ring.

Unique structure

Diphenylpropenyl group
The compound features a diphenylpropenyl group, which consists of two phenyl rings connected by a propenyl linker.

Potential applications

Pharmaceutical and agrochemical industries
Due to its unique structure and potential biological activity, this chemical may have applications in the pharmaceutical and agrochemical industries.

Precautions

Handling and usage
The compound should be handled and used with caution, as it may pose risks to human health and the environment if not managed properly.

Upstream product

• 120-72-9 indole 
• 87751-69-7 rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene 
• 121440-72-0 (E)-1,3-diphenylallyl methyl carbonate 
• 73930-97-9 3-acetoxy-1,3-diphenylpropene 

Relevant academic research and scientific papers

Chiral P,Olefin Ligands with Rotamers for Palladium-Catalyzed Asymmetric Allylic Substitution Reactions

We synthesized a series of phosphine-olefin-type chiral aminophosphines, and we confirmed that these each exists as two rotamers at the C(aryl)-N(amine) bond. We also investigated the ability of these aminophosphines to act as chiral ligands for Pd-catalyzed asymmetric allylic substitution reactions, such as the alkylation of allylic acetates with malonates or indoles, and we found they gave high enantio-selectivities (up to 98% ee).

Cinnamoyl amide type chiral P,olefin ligands for Pd-catalyzed reactions

We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and demonstrated Pd-catalyzed asymmetric allylic substitution reactions of indoles using (S,aS)-4d as a chiral ligand with high enantioselectivities (up to 98% ee). This journal is

Spiro indane-based phosphine-oxazolines as highly efficient P,N ligands for enantioselective Pd-catalyzed allylic alkylation of indoles and allylic etherification

A series of indane-based phosphine-oxazoline ligands with a spirocarbon stereogenic center were examined for palladium-catalyzed asymmetric allylic alkylation of indoles. Under optimized conditions, high yields (up to 98%) and enantioselectivities (up to

Chiral N-1-adamantyl-N-trans-cinnamylaniline type ligands: Synthesis and application to palladium-catalyzed asymmetric allylic alkylation of indoles

Such chiral phosphine-internal olefin hybrid type ligands as N-1-adamantyl-N-cinnamylaniline derivatives 1 with C(aryl)-N(amine) bond axial chirality were synthesized and utilized for the palladium-catalyzed asymmetric allylic alkylation of indoles to aff

Palladium-catalyzed asymmetric allylic alkylation of indoles by C-N bond axially chiral phosphine ligands

Abstract The palladium-catalyzed asymmetric allylic alkylation of indoles with 1,3-diphenyl-2-propenyl acetate using P/N-type ligands such as N-aryl indole, C-N bond axially chiral aminophosphine (aS)-L4, gave the desired products 1 in good yields and wit

Highly enantioselective Pd-catalyzed allylic alkylation of indoles using sulfur-MOP ligand

The preparation of various (R)-Sulfur-MOP ligands with aryl and alkyl substituents on sulfur, and the application of these ligands to Pd-catalyzed asymmetric allylic alkylation of indoles is reported. The sulfur substituent served as an effective stereoco