1265359-69-0

Upstream product

• 81574-69-8 2-bromo-4,6-dimethoxybenzaldehyde 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 
• 110-87-2 3,4-dihydro-2H-pyran 
• 1265359-67-8 2-bromo-4,6-dihydroxybenzaldehyde 

Downstream Products

• 1265359-85-0 2-(benzyloxy)-6-bromo-4-(tetrahydro-2H-pyran-2-yloxy)benzaldehyde 
• 1265358-15-3 2-(4-(benzyloxy)-1-hydroxy-6-(pyrazin-2-yloxy)-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetic acid 
• 1265362-19-3 ethyl 2-(4-(benzyloxy)-1-hydroxy-6-(pyrazin-2-yloxy)-1,3-dihydrobenzo[c][1,2]-oxaborol-3-yl)acetate 
• 1265355-45-0 2-(4-(benzyloxy)-1,6-dihydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetic acid 
• 1265359-94-1 ethyl 2-(4-(benzyloxy)-1,6-dihydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetate 
• 1265359-91-8 ethyl-(4-(benzyloxy)-1-hydroxy-6-(tetrahydro-2H-pyran-2-yloxy)-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetate 
• 1265359-88-3 2-(benzyloxy)-4-(tetrahydro-2H-pyran-2-yloxy)-6-(3,3,4,4-tetramethylborolan-1-yl)benzaldehyde 

Relevant academic research and scientific papers

BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY

Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.

TRISUBSTITUTED BORON-CONTAINING MOLECULES

This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.