126550-69-4

Usage

Chemical structure

Derivative of isoindole-1,3(2H)-dione
The basic structure is derived from an isoindole-1,3(2H)-dione compound, with modifications in its side chains.

Side chains

Pentenyl group and phenylmethoxymethyl group
The compound features a pentenyl group (five-carbon unsaturated hydrocarbon chain) and a phenylmethoxymethyl group (a phenyl ring attached to a methoxymethyl group) attached to the isoindole core.

Usage

Research and chemical synthesis
The compound is utilized in research environments and chemical synthesis processes, potentially serving as a building block for more complex molecules or as a target for various studies.

Properties and potential applications

May warrant further investigation
The properties and possible applications of 1H-Isoindole-1,3(2H)-dione, 2-[1-[(phenylmethoxy)methyl]-4-pentenyl]- are not fully detailed in the provided material, suggesting that further research and investigation may be necessary to uncover its full potential.

Upstream product

• 136918-14-4 phthalimide 
• 126550-68-3 (R)-1-(benzyloxy)hex-5-en-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 155418-40-9 (2S)-1-(benzyloxy)hex-5-en-2-ol 

Downstream Products

• 81702-31-0 (2S,5S)-pyrrolidine-2,5-dicarboxylic acid 
• 126550-73-0 N-Boc-2-(S)-benzoyloxymethyl-5-(S)-benzyloxy methylpyrrolidine 
• 126550-74-1 (2R,5S)-1-tert-butoxycarbonyl-2-benzyloxymethyl-5-benzyloxymethylpyrrolidine 
• 126550-72-9 (2S,5S)-2-benzyloxymethyl-5-benzoyloxymethylpyrrolidine 
• 138528-06-0 (2S,5S)-5-benzyloxymethyl-1-tert-butoxycarbonyl-2-hydroxymethylpyrrolidine 
• 126550-71-8 (S)-1-benzyloxy-2-benzoylaminohex-5-ene 
• 126550-70-7 (R)-1-Benzyloxymethyl-pent-4-enylamine 

Relevant academic research and scientific papers

VLA-4 inhibitor compounds

Compounds that selectively inhibit the binding of ligands to alpha4beta1 integrin (VLA-4) and methods for their preparation are disclosed. In one embodiment, compounds of the invention are represented by Formula I: As selective inhibitors of VLA-4 mediated cell adhesion, compounds of the present invention are useful in the treatment of conditions associated with such adhesion, including, but not limited to, such conditions as inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are pharmaceutical compositions, methods of inhibiting VLA-4 mediated cell adhesion and methods of treating conditions associated with LA-4 mediated cell adhesion, which involve compounds of Formula I.

CONCISE SYNTHESIS OF C2-SYMMETRIC TRANS-2,5-DIOXYMETHYLPYRROLIDINE DERIVATIVES BY NOVEL CYCLIZATION

Treatment of (S)-1-benzyloxy-2-benzoylaminohex-5-ene with iodine in aqueous acetonitrile furnished (2S,5S)-5-benzoyloxymethyl-2-bemzyloxymethylpyrrolidine stereoselectively in a single step.The product was converted into C2-symmetric (2S,5S)-2,5-dioxymethylpyrrolidines potentially utilizable as chiral auxiliaries and (2S,5S)-(-)-pyrrolidine-2,5-dicarboxylic acid isolated from marine alga Schizymenia dubyi.