12656-11-0
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Basic information
- Product Name: TINZAPARIN SODIUM
- Synonyms: TINZAPARIN SODIUM
- CAS NO:12656-11-0
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
- Mol File: 12656-11-0.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Dissolve 1.0 g in 10 mL of water R. The solution is clear (2.2.1) and not more intensely coloured than intensity 5 of the range of reference solutions of the most appropriate colour (2.2.2, Method II)
- Water Solubility: Soluble in water
- CAS DataBase Reference: TINZAPARIN SODIUM(CAS DataBase Reference)
- NIST Chemistry Reference: TINZAPARIN SODIUM(12656-11-0)
- EPA Substance Registry System: TINZAPARIN SODIUM(12656-11-0)
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Safety Data
- Hazard Codes: N/A
- Statements: R36/37/38-42/43:;
- Safety Statements: S22:; S24/S26/S36/37 :;
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 12656-11-0(Hazardous Substances Data)
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12656-11-0 Usage
Uses
Innohep (Pharmion).Clinical Use
Peri- and postoperative surgical thromboprophylaxis Treatment of DVT and pulmonary embolism Prevention of thrombus formation in extracorporeal circulation during HDDrug interactions
Potentially hazardous interactions with other drugs Analgesics: increased risk of bleeding with NSAIDs - avoid concomitant use with IV diclofenac; increased risk of haemorrhage with ketorolac - avoid concomitant use. Nitrates: anticoagulant effect reduced by infusions of glyceryl trinitrate. Use with care in patients receiving oral anticoagulants, platelet aggregation inhibitors, aspirin or dextran.Metabolism
Low molecular weight heparins are partially metabolised by desulphation and depolymerisation. The kidneys are the major site of tinzaparin excretion (approximately 70% based on animal studies).Check Digit Verification of cas no
The CAS Registry Mumber 12656-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,5 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.Calculate Digit Verification of CAS Registry Number 12656-11:
(7*1)+(6*2)+(5*6)+(4*5)+(3*6)+(2*1)+(1*1)=90
90 % 10 = 0
So 12656-11-0 is a valid CAS Registry Number.
12656-11-0Upstream product
12656-11-0Downstream Products
12656-11-0Related news
TINZAPARIN SODIUM (cas 12656-11-0) for thrombosis treatment and prevention during pregnancy☆08/17/2019
ObjectiveThis study was undertaken to assess the pharmacodynamic profile, safety, and efficacy of tinzaparin during pregnancy.detailed
A spectroscopic and molecular docking approach on the binding of TINZAPARIN SODIUM (cas 12656-11-0) with human serum albumin08/16/2019
Protein bound toxins are poorly removed by conventional extracorporeal therapies. Venous thromboembolism (VTE) is a major cause of morbidity and mortality in patients with cancer. The interaction between tinzaparin, an inhibitor of angiotensin converting enzyme and human serum albumin, a princip...detailed
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TINZAPARIN SODIUM
