126573-83-9Relevant articles and documents
Methanetricarboxylates as key reagents for the simple preparation of heteroarylcarboxamides with potential biological activity. Part 2 [1]. Reaction of methanetricarboxylates with 2-aminopyridine, 2-aminopyrimidine, 2-aminothiazole and 2-aminobenzothiazole
Kutyrev, Alexander,Kappe, Thomas
, p. 237 - 240 (2007/10/03)
The reaction of methanetricarboxylates 1a,b with 2-aminopyridine, 2- aminopyrimidine, 2-aminothiazole as well as 2-aminobenzothiazole yields corresponding heteroarylcarboxylic acid esters 2a,b, 5, 8, 11a,b. These heterocyclic esters were used as a starting material by the reaction with primary amines to obtaining a number of heteroarylcarboxylic amides 4a-j, 6, 10a,b, 13a-g bearing various substituents on the carboxamide group.
Base-Catalysed Rearrangement of Isoxazolinyl Heterocycles: Synthesis of Annelated Pyrimidines
Donati, Cosimo,Janowski, Wit K.,Prager, Rolf H.,Taylor, Max R.,Vilkins, Louise M.
, p. 2161 - 2169 (2007/10/02)
The rearrangement of a number of ethyl 2-(heterocyclic)-5-oxo-2,5-dihydroisoxazole-4-carboxylates by mild base is described, leading to new syntheses of the pyrimidoisoquinoline, pyrimidoquinoline, pyrimidobenzothiazole, pyrimido1,2-