126579-26-8

Basic information

• Product Name: METHYL-PIPERIDIN-4-YLMETHYL-AMINE
• Synonyms: N-METHYL(PIPERIDIN-4-YL)METHANAMINE;METHYL-PIPERIDIN-4-YLMETHYL-AMINE;N-methyl-1-piperidin-4-ylmethanamine dihydrochloride;Methyl-piperidin-4-ylMethy-alMine;N-Methyl-4-piperidinemethanamine;N-Methyl-1-(piperidin-4-yl)MethanaMine;4-(N-MethylaMinoMethyl)piperidine;methyl-(4-piperidylmethyl)amine
• CAS NO: 126579-26-8
• Molecular Formula: C7H16N2
• Molecular Weight: 128.22
• EINECS: 604-604-1
• Mol File: 126579-26-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 178℃
• Flash Point: 58℃
• Appearance: /
• Density: 0.861
• PKA: 10.57±0.10(Predicted)
• CAS DataBase Reference: METHYL-PIPERIDIN-4-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-PIPERIDIN-4-YLMETHYL-AMINE(126579-26-8)
• EPA Substance Registry System: METHYL-PIPERIDIN-4-YLMETHYL-AMINE(126579-26-8)

Safety Data

• Hazardous Substances Data: 126579-26-8(Hazardous Substances Data)

Usage

General Description

Methyl-piperidin-4-ylmethyl-amine is a chemical compound with the molecular formula C8H18N2. It is a derivative of piperidine and is utilized in the synthesis of various pharmaceuticals and organic compounds. This chemical is primarily used as an intermediate in the production of various medicinals and is also employed as a reagent in organic chemistry. Methyl-piperidin-4-ylmethyl-amine is a versatile compound that plays a crucial role in the development of a wide range of pharmaceuticals and other chemical products.

Upstream product

• 6843-37-4 N-methylisonicotinamide 
• 1903-69-1 piperidine-4-carboxylic acid methylamide 

Relevant articles and documents

Conformations of 1,p-Diazabicycloalkanes (Aza-Belted Piperidines)

Reduction of hexaalkylhydrazine dications produced from 2-methyl-1,2-diazabicyclooctane (4) by alkylation with bis-halides produces diazabicyclo compounds, for which we refer to the nitrogen-containing n atom bridge as the "aza-belt" in the title.The compound having a five-atom belt, 13, exists with a boat piperidine ring having an outward paramidalized nitrogen (13-1), a conclusion based on comparison of observed 1H NMR vicinal coupling constants with those calculated using MM2 geometries.MM2 predicts that 13-1 is favored over otherconformations by at least 2.6 kcal/mol. 13C NMR chemical shifts suggest a gross conformational change between 13 and the six-atom belt compounds, (6) and (10), for which MM2 predicts boat piperidine rings having inward pyramidalized nitrogens.PE and optical spectra of 6 and 13 are discussed. 16, the NH analogue of 13, undergoes unusually facile oxidation to give the aminal 1,5-diazatricyclo5,10>undecane (19).It is concluded from 1H NMR vicinal coupling constants and the unusually high-field absorption of H(3e) and C(3) that 19 exists both its aminal and piperidine six-membered rings in chair conformations, which is also the MM2 prediction.