1265916-66-2Relevant academic research and scientific papers
Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ1 receptor ligands with a (2-fluoroethyl) residue in 3-position
Maestrup, Eva Gro?e,Wiese, Christian,Schepmann, Dirk,Brust, Peter,Wünsch, Bernhard
experimental part, p. 393 - 405 (2011/02/27)
In order to develop a fluorinated radiotracer for imaging of σ1 receptors in the central nervous system a series of (2-fluoroethyl) substituted spirocyclic piperidines 3 has been prepared. In the key step of the synthesis 2-bromocinnamaldehyde
