1266112-20-2Relevant academic research and scientific papers
Thiophene and bioisostere derivatives as new MMP12 inhibitors
Badland, Matthew,Compre, Delphine,Courté, Karine,Dublanchet, Anne-Claude,Blais, Stéphane,Manage, Ajith,Peron, Guillaume,Wrigglesworth, Roger
, p. 528 - 530 (2011)
A new MMP12 inhibitor series has been identified containing a thiophene moiety. Different approaches have been considered to replace this potential toxicophore. α-Fluorothiophene derivatives were the most interesting compounds. Their synthesis is presente
