1266231-40-6

Basic information

• Product Name: methyl (1aR,4S,6aR,7aR)-5-benzyloctahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxylate
• Synonyms: methyl (1aR,4S,6aR,7aR)-5-benzyloctahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxylate
• CAS NO: 1266231-40-6
• Molecular Weight: 286.374
• Mol File: 1266231-40-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (1aR,4S,6aR,7aR)-5-benzyloctahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1aR,4S,6aR,7aR)-5-benzyloctahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxylate(1266231-40-6)
• EPA Substance Registry System: methyl (1aR,4S,6aR,7aR)-5-benzyloctahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxylate(1266231-40-6)

Safety Data

• Hazardous Substances Data: 1266231-40-6(Hazardous Substances Data)

Upstream product

• 1729-67-5 Methyl 2,3-dibromopropionate 
• 1266231-39-3 1-[(1R,3R,5R)-2-azabicyclo[3.1.0]hex-3-yl]-N-benzylmethanamine 
• 1266231-37-1 tert-butyl (1R,3R,5R)-3-[(benzylamino)methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate 
• 1148048-41-2 tert-butyl (1R,3R,5R)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate 
• 871727-37-6 2-tert-butyl 3-ethyl (1R,3R,5R)-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 
• 128811-31-4 tert-butyl (2R)-2-<<(tert-butyl)dimethylsilyloxy>methyl>-5-oxopyrrolidine-1-carboxylate 
• 1452400-40-6 tert-butyl (2R)-2-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2,3-dihydro-1H-pyrrole-1-carboxylate 
• 1091626-35-5 1-tert-butyl 2-ethyl (2R)-2,3-dihydro-1H-pyrrole-1,2-dicarboxylate 
• 144978-12-1 1-tert-butyl 2-ethyl (2R)-5-oxopyrrolidine-1,2-dicarboxylate 
• 1148048-42-3 tert-butyl (1R,3R,5R)-3-formyl-2-azabicyclo[3.1.0]hexane-2-carboxylate 

Downstream Products

• 1266231-48-4 tert-butyl [(1S)-2-{[(1S)-1-cyclohexyl-2-{(1aR,4S,6aR,7aR)-4-[(4R)-3,4-dihydro-2H-chromen-4-ylcarbamoyl]octahydro-5H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-5-yl}-2-oxoethyl]amino}-1-methyl-2-oxoethyl]methylcarbamate 

Relevant articles and documents

Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists

We recently reported the discovery of octahydropyrrolo[1,2-a]pyrazine A as a lead compound for an inhibitor of apoptosis proteins (IAP) antagonist. To develop IAP antagonists with favorable PK profiles, we designed novel tri-cyclic compounds, octahydro-1H