1266238-63-4

Basic information

• Product Name: ethyl 2,6-dichloro-5-fluoropyrimidine-4-carboxylate
• CAS NO: 1266238-63-4
• Molecular Weight: 239.033
• Mol File: 1266238-63-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 2,6-dichloro-5-fluoropyrimidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,6-dichloro-5-fluoropyrimidine-4-carboxylate(1266238-63-4)
• EPA Substance Registry System: ethyl 2,6-dichloro-5-fluoropyrimidine-4-carboxylate(1266238-63-4)

Safety Data

• Hazardous Substances Data: 1266238-63-4(Hazardous Substances Data)

Upstream product

• 703-95-7 5-fluoro-2,6-dihydroxypyrimidine-4-carboxylic acid 
• 132214-26-7 ethyl 5-fluoroorotic acid 
• 703-95-7 5-fluoroorotic acid 

Downstream Products

• 1266238-52-1 (S)-5'-fluoro-2-[2-(4-fluoro-phenyl)-morpholin-4-yl]-1-methyl-1H-[4,4']bipyrimidinyl-6-one 

Relevant articles and documents

ESTER AND CARBONATE PYRIMIDINE COMPOUNDS AS JAK KINASE INHIBITORS

The invention provides compounds of formula (I): (I) or pharmaceutically-acceptable salts thereof, that are inhibitors of Janus kinases and release an active metabolite in vivo. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat inflammatory skin diseases and other diseases.

PYRIMIDINE COMPOUND AS JAK KINASE INHIBITOR

The invention provides a compound of formula (I): or a pharmaceutically-acceptable salt thereof, that is an inhibitor of JAK kinases. The invention also provides pharmaceutical compositions comprising such compound, a crystalline form, methods of using such compound to treat inflammatory skin diseases and other diseases, and processes and intermediates useful for preparing such compound.

ARYL SUBSTITUTED PYRIMIDINES FOR USE IN INFLUENZA VIRUS INFECTION

The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.