126632-35-7

Basic information

• Product Name: L-Glutamic acid, N-(4-amino-3-fluorobenzoyl)-, diethyl ester
• CAS NO: 126632-35-7
• Molecular Formula: C16H21FN2O5
• Molecular Weight: 340.352
• Mol File: 126632-35-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-(4-amino-3-fluorobenzoyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-(4-amino-3-fluorobenzoyl)-, diethyl ester(126632-35-7)
• EPA Substance Registry System: L-Glutamic acid, N-(4-amino-3-fluorobenzoyl)-, diethyl ester(126632-35-7)

Safety Data

• Hazardous Substances Data: 126632-35-7(Hazardous Substances Data)

Upstream product

• 157665-51-5 3-fluoro-4-nitrobenzoyl chloride 
• 1118-89-4 diethyl-L-glutamate hydrochloride 
• 403-21-4 3-fluoro-4-nitrobenzoic acid 
• 126632-34-6 diethyl N-(3-fluoro-4-nitrobenzoyl)-L-glutamate 

Downstream Products

• 112888-93-4 diethyl N-<3-fluoro-4-(prop-2-ynylamino)benzoyl>-L-glutamate 
• 129175-69-5 (S)-2-(3-Fluoro-4-methylamino-benzoylamino)-pentanedioic acid diethyl ester 
• 129175-47-9 diethyl N-<4--6-quinazolinyl>methyl>-N-(3-acetoxypropyl)amino>-3-fluorobenzoyl>-L-glutamate 
• 129175-46-8 (S)-2-(4-{(2-Acetoxy-ethyl)-[3-(2,2-dimethyl-propionyloxymethyl)-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl]-amino}-3-fluoro-benzoylamino)-pentanedioic acid diethyl ester 
• 129193-69-7 (S)-2-{3-Fluoro-4-[(2-fluoro-ethyl)-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 129175-29-7 (S)-2-{3-Fluoro-4-[(3-hydroxy-propyl)-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid 
• 129175-28-6 (S)-2-{3-Fluoro-4-[(2-hydroxy-ethyl)-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid 
• 129175-27-5 (S)-2-{3-Fluoro-4-[(2-fluoro-ethyl)-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid 
• 129175-23-1 (S)-2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid 
• 129193-68-6 (S)-2-(4-{Allyl-[3-(2,2-dimethyl-propionyloxymethyl)-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl]-amino}-3-fluoro-benzoylamino)-pentanedioic acid diethyl ester 
• 129193-67-5 (S)-2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 129175-45-7 (S)-2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-3-fluoro-benzoylamino}-pentanedioic acid diethyl ester 
• 129175-44-6 (S)-2-{3-Fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 112888-30-9 (S)-2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid 

Relevant articles and documents

Synthesis and biological activity of open-chain analogues of 5,6,7,8- tetrahydrofolic acid-potential antitumor agents

This study describes the synthesis and in vitro antitumor activity of inhibitors of purine de novo biosynthesis that are analogues of N-[4-[[3- (2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]benzoyl-L-glutamic acid (5-DACTHF). Benzene ring subs