126640-92-4Relevant academic research and scientific papers
Concise Total Synthesis of (+)-Aphanorphine
Wang, Cheng,Guan, Yukun
supporting information, p. 913 - 916 (2021/04/19)
A concise total synthesis of (+)-aphanorphine is described. The key features of the strategy include a Pd-catalyzed intermolecular trimethylenemethane [3+2]-cycloaddition to form ring C and a Co-catalyzed radical cyclization through a hydrogen-atom transf
Enantioconvergent synthesis of (+)-aphanorphine via asymmetric pd-catalyzed alkene carboamination
Mai, Duy N.,Rosen, Brandon R.,Wolfe, John P.
supporting information; experimental part, p. 2932 - 2935 (2011/07/30)
A concise asymmetric synthesis of (+)-aphanorphine has been achieved via a new enantioconvergent strategy. A racemic γ-aminoalkene derivative is transformed into a 1:1 mixture of enantiomerically enriched diastereomers using an asymmetric Pd-catalyzed car
Enantiocontrolled Synthesis of (+)-Aphanorphine from (R)-O-Benzylglycidol: Assignment of Absolute Configuration
Takano, Seiichi,Inomata, Kohei,Sato, Tsutomu,Ogasawara, Kunio
, p. 1591 - 1592 (2007/10/02)
Aphanorphine, a novel 3-benzazepine alkaloid isolated from the freshwater blue-green alga Aphanizomenon flos-aquae, has been syntesized in the antipodal forms starting from (R)-O-benzylglycidol to establish the absolute configuration of the natural produc
