126642-45-3Relevant academic research and scientific papers
Spiro hydantoin aldose reductase inhibitors derived from 8-aza-4-chromanones
Sarges,Goldstein,Welch,Swindell,Siegel,Beyer
, p. 1859 - 1865 (2007/10/02)
A series of spiro hydantoins derived from 8-azachromanones (2,3-dihydro-4H-pyrano[2,3-b]pyridin-4-ones) has been prepared and tested for aldose reductase inhibitory activity. The standard Bucherer-Bergs conditions had to be drastically modified to increas
