126644-88-0Relevant academic research and scientific papers
Zn/CuI-mediated coupling of alkyl halides with vinyl sulfones, vinyl sulfonates, and vinyl sulfonamides
Zhao, Matthew M.,Qu, Chuanxing,Lynch, Joseph E.
, p. 6944 - 6947 (2007/10/03)
A novel high-yielding Zn/CuI-mediated coupling method of alkyl halides with vinyl sulfones, vinyl sulfonates, and vinyl sulfonamides is described. This protocol is applicable for primary, secondary, and tertiary alkyl iodides and bromides. Alkyl chlorides
Indium as a radical initiator in aqueous media: Intermolecular alkyl radical addition to C=N and C=C bond
Miyabe, Hideto,Ueda, Masafumi,Nishimura, Azusa,Naito, Takeaki
, p. 4227 - 4235 (2007/10/03)
The carbon-carbon bond-forming method in aqueous media was investigated by using indium as a single-electron transfer radical initiator. The indium-mediated intermolecular alkyl radical addition to imine derivatives and electron-deficient C=C bond proceeded effectively.
Indium-mediated intermolecular alkyl radical addition to electron-deficient C=N bond and C=C bond in water
Miyabe, Hideto,Ueda, Masafumi,Nishimura, Azusa,Naito, Takeaki
, p. 131 - 133 (2007/10/03)
(matrix presented) The intermolecular alkyl radical addition to imine derivatives was studied in aqueous media by using indium as a single-electron-transfer radical initiator. The one-pot reaction based on radical addition to glyoxylic hydrazone provided a convenient method for preparing the α-amino acids. The indium-mediated radical addition to an electron-deficient C=C bond also proceeded effectively to provide the new carbon-carbon bond-forming method in aqueous media.
Directed Lithiation of Chlorobenzenes. Regioselectivity and Application to a Short Synthesis of Benzocyclobutenes
Iwao, Masatomo
, p. 3622 - 3627 (2007/10/02)
Chlorobenzene and its OMe, OSiMe2-t-Bu, and Cl derivatives 1 were lithiated with high regioselectivity ortho to chlorine by treatment with sec-BuLi in THF at -105 deg C without complications due to benzyne formation.The lithio species thus generated under
