126654-52-2

Basic information

• Product Name: 1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy-
• Synonyms: 1(3H)-Isobenzofuranone,5-(3,7-dimethyl-5-oxo-2,6-octadienyl)-4-hydroxy-6-methoxy-, (E)-;1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadienyl]-4-hydroxy-6-methoxy- (9CI);Hericenone A
• CAS NO: 126654-52-2
• Molecular Formula: C19H22 O5
• Molecular Weight: 330.381
• Mol File: 126654-52-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy-(126654-52-2)
• EPA Substance Registry System: 1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy-(126654-52-2)

Safety Data

• Hazardous Substances Data: 126654-52-2(Hazardous Substances Data)

Usage

General Description

1(3H)-Isobenzofuranone, 5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy- is a chemical compound with the molecular formula C18H20O5. It is a naturally occurring compound found in various plant species and exhibits antioxidant and anti-inflammatory properties. 1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy- has been studied for its potential therapeutic applications, including its ability to inhibit the growth of certain cancer cells and its potential to protect against neurodegenerative diseases. Additionally, it has been investigated for its potential use in skincare products due to its antioxidant and anti-aging properties. Overall, 1(3H)-Isobenzofuranone, 5-[(2E)-3, 7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxy- is a compound with diverse potential applications in various fields, including medicine and cosmetics.

Upstream product

• 1610729-85-5 C₂₁H₂₈O₆ 
• 1610729-83-3 C₂₃H₃₆O₃Si 
• 1610729-82-2 C₁₇H₂₂O₃ 
• 1610729-84-4 (E)-tert-butyl((2,6-dimethyl-8-(tributylstannyl)octa-2,6-dien-4-yl)oxy)dimethylsilane 
• 1610729-71-9 (E)-5-(3,7-dimethyl-5-oxoocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-70-8 (E)-5-(5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-69-5 C₂₇H₄₆O₆Si 
• 1610729-68-4 (E)-6-(5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-yl)-5-methoxy-7-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-67-3 (E)-5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-ol 
• 143537-56-8 3-Hydroxy-5-methoxy-4-(2-oxo-ethyl)-phthalic acid dimethyl ester 
• 143537-46-6 4-Allyl-5-hydroxy-3-methoxy-phthalic acid dimethyl ester 
• 143537-59-1 5-((E)-4-Bromo-3-methyl-but-2-enyl)-4-hydroxy-6-methoxy-3H-isobenzofuran-1-one 
• 143537-58-0 4-Hydroxy-5-((E)-4-hydroxy-3-methyl-but-2-enyl)-6-methoxy-3H-isobenzofuran-1-one 
• 143537-60-4 4-Hydroxy-6-methoxy-5-{(E)-3-methyl-4-[2-(2-methyl-propenyl)-[1,3]dithian-2-yl]-but-2-enyl}-3H-isobenzofuran-1-one 

Relevant articles and documents

Divergent synthesis of bioactive resorcinols isolated from the fruiting bodies of hericium erinaceum: Total syntheses of hericenones A, B, and I, hericenols B-D, and erinacerins A and B

Total syntheses of 5'- and 7'-oxidized geranyl resorcylates isolated from the fruiting bodies of Hericium erinaceum and the submerged cultures of a Stereum species were achieved. Our synthesis features derivatization of a suitably functionalized 5'-oxidized geranyl phthalide as a common intermediate, which was obtained by Stille coupling between the phthalide core and the side chain, into a series of natural products by divergent functional group manipulations. The crucial C5'-oxygen functionality was installed at the initial stage by alkylation by an α-cyano ethoxyethyl ether. From a common synthetic intermediate, eight total syntheses including hericenones A, B, and I, hericenols B-D, and erinacerins A and B were achieved (hericenol B and erinacerin B were synthesized as racemates). The structure of hericenone B established in the isolation paper was unambiguously revised as the carbonyl regioisomer at the lactam moiety.