126654-52-2

Usage

Uses

Used in Pharmaceutical Industry:
1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxyis used as a potential therapeutic agent for its ability to inhibit the growth of certain cancer cells. Its anti-inflammatory properties also make it a candidate for the treatment of various inflammatory conditions.
Used in Neuroprotection:
1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxyis used as a potential neuroprotective agent due to its ability to protect against neurodegenerative diseases. Its antioxidant properties may help reduce oxidative stress and protect neurons from damage.
Used in Skincare Products:
1(3H)-Isobenzofuranone,5-[(2E)-3,7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxyis used as an ingredient in skincare products for its antioxidant and anti-aging properties. It may help protect the skin from environmental damage, reduce the appearance of fine lines and wrinkles, and promote a more youthful complexion.
Overall, 1(3H)-Isobenzofuranone, 5-[(2E)-3, 7-dimethyl-5-oxo-2,6-octadien-1-yl]-4-hydroxy-6-methoxyis a compound with diverse potential applications in various fields, including medicine and cosmetics. Its antioxidant, anti-inflammatory, and anticancer properties make it a promising candidate for further research and development in these areas.

Upstream product

• 143537-60-4 4-Hydroxy-6-methoxy-5-{(E)-3-methyl-4-[2-(2-methyl-propenyl)-[1,3]dithian-2-yl]-but-2-enyl}-3H-isobenzofuran-1-one 
• 1610729-85-5 C₂₁H₂₈O₆ 
• 1610729-83-3 C₂₃H₃₆O₃Si 
• 1610729-82-2 C₁₇H₂₂O₃ 
• 1610729-84-4 (E)-tert-butyl((2,6-dimethyl-8-(tributylstannyl)octa-2,6-dien-4-yl)oxy)dimethylsilane 
• 1610729-71-9 (E)-5-(3,7-dimethyl-5-oxoocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-70-8 (E)-5-(5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-69-5 C₂₇H₄₆O₆Si 
• 1610729-68-4 (E)-6-(5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-yl)-5-methoxy-7-(methoxymethoxy)isobenzofuran-1(3H)-one 
• 1610729-67-3 (E)-5-((tert-butyldimethylsilyl)oxy)-3,7-dimethylocta-2,6-dien-1-ol 
• 143537-57-9 3-Hydroxy-5-methoxy-4-((E)-3-methyl-4-oxo-but-2-enyl)-phthalic acid dimethyl ester 
• 143537-55-7 3,5-Dimethoxy-4-(2-oxo-ethyl)-phthalic acid dimethyl ester 
• 143537-47-7 dimethyl 4-allyl-3,5-dimethoxyphthalate 
• 143537-56-8 3-Hydroxy-5-methoxy-4-(2-oxo-ethyl)-phthalic acid dimethyl ester 

Relevant academic research and scientific papers

Divergent synthesis of bioactive resorcinols isolated from the fruiting bodies of hericium erinaceum: Total syntheses of hericenones A, B, and I, hericenols B-D, and erinacerins A and B

Total syntheses of 5'- and 7'-oxidized geranyl resorcylates isolated from the fruiting bodies of Hericium erinaceum and the submerged cultures of a Stereum species were achieved. Our synthesis features derivatization of a suitably functionalized 5'-oxidized geranyl phthalide as a common intermediate, which was obtained by Stille coupling between the phthalide core and the side chain, into a series of natural products by divergent functional group manipulations. The crucial C5'-oxygen functionality was installed at the initial stage by alkylation by an α-cyano ethoxyethyl ether. From a common synthetic intermediate, eight total syntheses including hericenones A, B, and I, hericenols B-D, and erinacerins A and B were achieved (hericenol B and erinacerin B were synthesized as racemates). The structure of hericenone B established in the isolation paper was unambiguously revised as the carbonyl regioisomer at the lactam moiety.

First unambiguous total synthesis of hericenone A: Proposed structure revised

Hericenone A has been synthesized by an unambiguous route involving a Diels-Alder reaction and the well known regioselective NaBH4-reduction of the phthalates.