1266547-54-9Relevant academic research and scientific papers
Development of enantioselective synthetic routes to (-)-Kinamycin F and (-)-lomaiviticin aglycon
Woo, Christina M.,Gholap, Shivajirao L.,Lu, Liang,Kaneko, Miho,Li, Zhenwu,Ravikumar, P. C.,Herzon, Seth B.
, p. 17262 - 17273,12 (2020/09/02)
The development of enantioselective synthetic routes to (-)-kinamycin F (9) and (-)-lomaiviticin aglycon (6) are described. The diazotetrahydrobenzo[b] fluorene (diazofluorene) functional group of the targets was prepared by fluoride-mediated coupling of
11-step enantioselective synthesis of (-)-lomaiviticin aglycon
Herzon, Seth B.,Lu, Liang,Woo, Christina M.,Gholap, Shivajirao L.
supporting information; experimental part, p. 7260 - 7263 (2011/06/23)
Lomaiviticins A and B are complex antitumor antibiotics that were isolated from a strain of Micromonospora. A confluence of several unusual structural features renders the lomaiviticins exceedingly challenging targets for chemical synthesis. We report an
