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1266666-28-7

10-(cyclohexylmethoxy)decan-1-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1266666-28-7 Structure

  • Basic information

    1. Product Name: 10-(cyclohexylmethoxy)decan-1-ol
    2. Synonyms: 10-(cyclohexylmethoxy)decan-1-ol
    3. CAS NO:1266666-28-7
    4. Molecular Formula:
    5. Molecular Weight: 270.456
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1266666-28-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 10-(cyclohexylmethoxy)decan-1-ol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 10-(cyclohexylmethoxy)decan-1-ol(1266666-28-7)
    11. EPA Substance Registry System: 10-(cyclohexylmethoxy)decan-1-ol(1266666-28-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1266666-28-7(Hazardous Substances Data)

1266666-28-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1266666-28-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,6,6,6 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1266666-28:
(9*1)+(8*2)+(7*6)+(6*6)+(5*6)+(4*6)+(3*6)+(2*2)+(1*8)=187
187 % 10 = 7
So 1266666-28-7 is a valid CAS Registry Number.

1266666-28-7Relevant articles and documents

IMIDAMIDE SPHINGOSINE KINASE INHIBITORS

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Page/Page column 20; 26, (2012/09/05)

Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 and SphK2) are provided. The compounds can prevent angiogenesis in tumors.

Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells

Kennedy, Andrew J.,Mathews, Thomas P.,Kharel, Yugesh,Field, Saundra D.,Moyer, Morgan L.,East, James E.,Houck, Joseph D.,Lynch, Kevin R.,MacDonald, Timothy L.

, p. 3524 - 3548 (2011/07/07)

Sphingosine 1-phosphate (S1P) is a bioactive lipid that has been identified as an accelerant of cancer progression. The sphingosine kinases (SphKs) are the sole producers of S1P, and thus, SphK inhibitors may prove effective in cancer mitigation and chemosensitization. Of the two SphKs, SphK1 overexpression has been observed in a myriad of cancer cell lines and tissues and has been recognized as the presumptive target over that of the poorly characterized SphK2. Herein, we present the design and synthesis of amidine-based nanomolar SphK1 subtype-selective inhibitors. A homology model of SphK1, trained with this library of amidine inhibitors, was then used to predict the activity of additional, more potent, inhibitors. Lastly, select amidine inhibitors were validated in human leukemia U937 cells, where they significantly reduced endogenous S1P levels at nanomolar concentrations.

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