1266701-52-3Relevant academic research and scientific papers
Design and synthesis of potent macrocyclic renin inhibitors
Sund, Christian,Belda, Oscar,Wiktelius, Daniel,Sahlberg, Christer,Vrang, Lotta,Sedig, Susanne,Hamelink, Elizabeth,Henderson, Ian,Agback, Tatiana,Jansson, Katarina,Borkakoti, Neera,Derbyshire, Dean,Eneroth, Anders,Samuelsson, Bertil
scheme or table, p. 358 - 362 (2011/02/27)
Two types of P1-P3-linked macrocyclic renin inhibitors containing the hydroxyethylene isostere (HE) scaffold just outside the macrocyclic ring have been synthesized. An aromatic or aliphatic substituent (P3sp) was introduced in the macrocyclic ring aiming
