126751-09-5

Upstream product

• 22019-49-4 2-bromo-1-(4-chloro-3-nitrophenyl)ethanone 
• 17356-08-0 thiourea 
• 476660-57-8 4-(4-chloro-3-nitrophenyl)-1,3-thiazole-2-amine hydrobromide 

Downstream Products

• 126751-12-0 2-Amino-4-(4-amino-3-nitrophenyl)thiazole 
• 126751-10-8 2-(N-Ethoxycarbonylthiocarboxamido)amino-5-(4-chloro-3-nitrophenyl)thiazole 
• 476660-59-0 4-(4-chloro-3-nitrophenyl)-1,3-thiazole 
• 126751-11-9 2-Acetamido-4-(4-chloro-3-nitrophenyl)thiazole 
• 126751-19-7 [4-(4-Chloro-3-nitro-phenyl)-thiazol-2-yl]-carbamic acid ethyl ester 

Relevant academic research and scientific papers

3-QUINOLINE-2-(1H)-YLIDENEINDOLIN-2-ONE DERIVATIVES

There is provided medicaments, particularly a vascular endothelial growth factor (VEGF) inhibitor which is useful as a therapeutic drug for solid tumors, diabetic retinopathy and the like diseases in which angiogenesis is taking a role. That is, since a novel 3-quinolin-2(1H)-ylideneindolin-2-one derivative or a salt thereof has good VEGF inhibitory action, angiogenesis inhibitory action and anti-tumor action, it is useful as ideal VEGF inhibitor, angiogenesis inhibitor and anti-tumor agent.