1267588-76-0

Basic information

• Product Name: (3R,4R)-methyl 2-oxo-4-pentyl-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate
• CAS NO: 1267588-76-0
• Molecular Weight: 302.37
• Mol File: 1267588-76-0.mol

Chemical Properties

• CAS DataBase Reference: (3R,4R)-methyl 2-oxo-4-pentyl-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-methyl 2-oxo-4-pentyl-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate(1267588-76-0)
• EPA Substance Registry System: (3R,4R)-methyl 2-oxo-4-pentyl-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate(1267588-76-0)

Safety Data

• Hazardous Substances Data: 1267588-76-0(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 

Relevant articles and documents

Organocatalytic Functionalization of carboxylic acids: Isothiourea- catalyzed asymmetric intra- and intermolecular Michael addition-lactonizations

Tetramisole promotes the catalytic asymmetric intramolecular Michael addition-lactonization of a variety of enone acids, giving carbo- and heterocyclic products with high diastereo- and enantiocontrol (up to 99:1 dr, up to 99% ee) that are readily derivatized to afford functionalized indene and dihydrobenzofuran carboxylates. Chiral isothioureas also promote the catalytic asymmetric intermolecular Michael addition-lactonization of arylacetic acids and α-keto-β,γ-unsaturated esters, giving anti-dihydropyranones with high diastereo- and enantiocontrol (up to 98:2 dr, up to 99% ee).