1267589-13-8

Basic information

• Product Name: (E)-2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetic acid
• Synonyms: (E)-2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetic acid
• CAS NO: 1267589-13-8
• Molecular Weight: 234.252
• Mol File: 1267589-13-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetic acid(1267589-13-8)
• EPA Substance Registry System: (E)-2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetic acid(1267589-13-8)

Safety Data

• Hazardous Substances Data: 1267589-13-8(Hazardous Substances Data)

Upstream product

• 88521-73-7 ethyl 2-(2-formyl-4-methylphenoxy)acetate 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 1267589-56-9 (E)-ethyl 2-(4-methyl-2-(3-oxobut-1-en-1-yl)phenoxy)acetate 

Relevant articles and documents

Organocatalytic Functionalization of carboxylic acids: Isothiourea- catalyzed asymmetric intra- and intermolecular Michael addition-lactonizations

Tetramisole promotes the catalytic asymmetric intramolecular Michael addition-lactonization of a variety of enone acids, giving carbo- and heterocyclic products with high diastereo- and enantiocontrol (up to 99:1 dr, up to 99% ee) that are readily derivatized to afford functionalized indene and dihydrobenzofuran carboxylates. Chiral isothioureas also promote the catalytic asymmetric intermolecular Michael addition-lactonization of arylacetic acids and α-keto-β,γ-unsaturated esters, giving anti-dihydropyranones with high diastereo- and enantiocontrol (up to 98:2 dr, up to 99% ee).