1267622-99-0

Basic information

• Product Name: C₁₁H₇NO
• Synonyms: C₁₁H₇NO
• CAS NO: 1267622-99-0
• Molecular Weight: 169.183
• Mol File: 1267622-99-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₁H₇NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₇NO(1267622-99-0)
• EPA Substance Registry System: C₁₁H₇NO(1267622-99-0)

Safety Data

• Hazardous Substances Data: 1267622-99-0(Hazardous Substances Data)

Upstream product

• 14235-81-5 4-Ethynylaniline 
• 471-25-0 Propiolic acid 

Downstream Products

• 1267623-47-1 C₁₉H₂₁N₇O₅ 
• 1267623-24-4 C₁₈H₁₄N₄O 
• 1267623-23-3 C₁₅H₁₄N₄O₃ 
• 1267623-25-5 C₁₅H₁₄N₄O₃ 
• 1267623-31-3 C₁₅H₁₄N₄O₃ 
• 1267623-30-2 C₁₈H₁₄N₄O 
• 1267623-29-9 C₁₅H₁₄N₄O₃ 
• 1267623-49-3 ethyl 2-[4-({4-[1-(2-ethoxy-2-oxoethyl)-1H-1,2,3-triazol-4-yl]phenyl}carbamoyl)-1H-1,2,3-triazol-1-yl]acetate 
• 1267623-48-2 ethyl 2-(4-{[4-(1-benzyl-1H-1,2,3-triazol-4-yl)phenyl]carbamoyl}-1H-1,2,3-triazol-1-yl)acetate 
• 1267623-46-0 C₂₂H₂₁N₇O₃ 
• 1267623-45-9 C₂₅H₂₁N₇O 
• 1267623-44-8 C₂₂H₂₁N₇O₃ 
• 1267623-43-7 C₁₉H₂₁N₇O₅ 
• 1267623-42-6 C₂₂H₂₁N₇O₃ 

Relevant articles and documents

Synthesis and in vitro evaluation of potential anticancer activity of mono- and bis-1,2,3-triazole derivatives of bis-alkynes

In order to find new molecules with cytotoxic activity against cancer cells, we prepared bis-akyne amides derived from propiolic acid. The bis-alkynes were then transformed in their mono-1,2,3-triazole analogs onto the amide side, due to its greater reactivity, using a catalyst-free Huisgen's reaction. The mono-triazoles were then subjected to the copper (I)-catalyzed version of the previous reaction (CuAAC), using a supported catalyst, to produce bis-triazoles. All products were obtained pure after simple trituration or filtration procedures. All synthetic compounds were tested in vitro for their cytotoxic activity using B16 melanoma cells. Four compounds (7, 23, 25 and 33) showed activities in the micromolar range (21 μM) whereas three compounds (3, 22 and 38) presented activity at low micromolar concentrations (10 μM), and two analogs (2 and 13) were active at nanomolar levels (1 μM).