1267636-45-2Relevant academic research and scientific papers
Enantioselective haloetherification by asymmetric opening of meso -halonium ions
Hennecke, Ulrich,Mueller, Christian H.,Froehlich, Roland
supporting information; experimental part, p. 860 - 863 (2011/05/03)
A new approach to enantioselective haloetherification reactions via desymmetrization of in situ-generated meso-halonium ions is described. The combination of N-haloamides as a halogen source and sodium salts of chiral phosphoric acids as catalysts can be used for the cyclization of symmetrical ene-diol substrates, yielding the haloetherification products under practical conditions in enantioenriched form.(Figure Presented)
