1267640-25-4Relevant articles and documents
Efficient access to new chemical space through flow-construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions
Bogdan, Andrew R.,James, Keith
, p. 14506 - 14512 (2011/03/20)
A series of 12- to 22-membered macrocycles, with druglike functionality and properties, have been generated by using a simple and efficient copper-catalyzed azide-acetylene cycloaddition reaction, conducted in flow in high-temperature copper tubing, under