126766-82-3Relevant academic research and scientific papers
Convenient synthesis of 2,2-and 4,4-methylenebisphenols with bulky alkyl substituents and evaluation of their antioxidant activity
Buravlev, Evgeny V.,Chukicheva, Irina Yu.,Borisenkov, Mikhail F.,Kutchin, Aleksandr V.
, p. 3670 - 3676,7 (2012)
The work is devoted to a convenient procedure of the synthesis of 2,2-and 4,4-methylenebisphenols with alkyl substituents in heterogeneous catalysis. This compounds were obtained with yields up to 87% by reflux of 2,4-or 2,6-dialkylphenols with HCHO in n-octane in the presence of KSF clay. We found that the antioxidant activity on DPPH test for two novel methylenebisphenols having isobornyl fragments was comparable with control drugs.
