126781-91-7

Basic information

• Product Name: Cyclohexanecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester
• CAS NO: 126781-91-7
• Molecular Formula: C14H28O3Si
• Molecular Weight: 272.46
• Mol File: 126781-91-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester(126781-91-7)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester(126781-91-7)

Safety Data

• Hazardous Substances Data: 126781-91-7(Hazardous Substances Data)

Upstream product

• 133642-20-3 4-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester 
• 3685-22-1 4-hydroxycyclohexanecarboxylic acid 
• 288-32-4 1H-imidazole 
• 3618-03-9 methyl 4-hydroxycyclohexanecarboxylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 478841-18-8 2-((4-hydroxycyclohexyl)methyl)isoindoline-1,3-dione 
• 189753-93-3 (cis/trans)-4-<(tert-Butyldimethylsilyl)oxy>cyclohexanemethanol 

Relevant articles and documents

Catalytic Transfer Hydrogenation of Arenes and Heteroarenes

Transfer hydrogenation reactions are of great interest to reduce diverse molecules under mild reaction conditions. To date, this type of reaction has only been successfully applied to alkenes, alkynes and polarized unsaturated compounds such as ketones, imines, pyridines, etc. The reduction of benzene derivatives by transfer hydrogenation has never been described, which is likely due to the high energy barrier required to dearomatize these compounds. In this context, we have developed a catalytic transfer hydrogenation reaction for the reduction of benzene derivatives and heteroarenes to form complex 3-dimensional scaffolds bearing various functional groups at room temperature without needing compressed hydrogen gas.

Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

CYCLICALLY SUBSTITUTED 3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF

The present application relates to novel 4-cycloalkyl- and 4-heterocycloalkyl-3,5-dicyano-2-thio-pyridine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.