126801-51-2

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 70-55-3 toluene-4-sulfonamide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 13362-71-5 bis-((1Ξ,2E)-3-phenyl-allylidene)-hydrazine 
• 121033-92-9 (E)-1-methyl-4-((3-phenylprop-1-en-1-yl)sulfonyl)benzene 
• 2458-26-6 5-phenyl-1H-pyrazole 
• 863711-35-7 2-(3-chloro-phenyl)-5-styryl-2H-tetrazole 
• 29475-88-5 trans-2-styrylindole 
• 1428882-38-5 (E)-2-(3,4-dimethylphenyl)-1-styrylisoindoline 
• 1428882-46-5 (E)-5-bromo-2-(3,4-dimethylphenyl)-1-styrylisoindoline 
• 1428882-45-4 (E)-5-chloro-2-(3,4-dimethylphenyl)-1-styrylisoindoline 
• 1428882-44-3 (E)-2-(3,4-dimethylphenyl)-5-fluoro-1-styrylisoindoline 
• 1428882-43-2 (E)-2-(4-chlorophenyl)-1-styrylisoindoline 
• 1428882-42-1 (E)-2-phenyl-1-styrylisoindoline 
• 1428882-41-0 (E)-1-styryl-2-(m-tolyl)isoindoline 
• 1428882-40-9 (E)-2-(4-methoxyphenyl)-1-styrylisoindoline 
• 1428882-39-6 (E)-1-styryl-2-(p-tolyl)isoindoline 

Relevant academic research and scientific papers

Lewis Acid Catalyzed [4 + 2] Cycloaddition of N-Tosylhydrazones with ortho-Quinone Methides

A formal [4 + 2] cycloaddition of N-tosylhydrazones with ortho-quinone methides was developed, affording the facile synthesis of diverse 1,3-oxazine derivatives under mild conditions. In this transformation, N-tosylhydrazones are used as a 1,2-dipole synt

Divergent Synthesis of Vinyl-, Benzyl-, and Borylsilanes: Aryl to Alkyl 1,5-Palladium Migration/Coupling Sequences

Organosilicon compounds have been extensively utilized both in industry and academia. Studies on the syntheses of diverse organosilanes is highly appealing. Through-space metal/hydrogen shifts allow functionalization of C?H bonds at a remote site, which are otherwise difficult to achieve. However, until now, an aryl to alkyl 1,5-palladium migration process seems to have not been presented. Reported herein is the remote olefination, arylation, and borylation of a methyl group on silicon to access diverse vinyl-, benzyl-, and borylsilanes, constituting a unique C(sp3)?H transformation based on a 1,5-palladium migration process.

One-Pot Reaction between N-Tosylhydrazones and 2-Nitrobenzyl Bromide: Route to NH-Free C2-Arylindoles

A one-pot Barluenga coupling between N-tosylhydrazones and nitro-benzyl bromide, followed by deoxygenation of ortho-nitrostyrenes, and subsequent cyclization has been developed, providing a new way to synthesize various C2-arylindoles. This method exhibits a good substrate scope and functional group tolerance, and it allows an access to NH-free indoles, which can present a potential utility in medicinal chemistry applications.

TETRAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONITS

The present invention relates to new compounds of formula I, wherein P, Q, X1, X2, X3, X4, R1, R2, m and p, are as defined as in formula I, or salts, solvates or solvated salts thereof, processes for their preparation and new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds, and to the use of said compounds in therapy.

The Photolysis of p-Tosylhydrazones of Aryl and α,β-Unsaturated Carbonyl Compounds

The ultraviolet irradiation of p-tosylhydrazones of aryl and α,β-unsaturated carbonyl compounds yields azines and sulphones and exhibits a strong solvent effect.Styryl substrates afford α,β-unsaturated sulphones, the shift of the olefinic double bond probably arising through an intermediate azoderivative.The p-tosylhydrazone of benzylideneacetone is to a great extent transformed to the cis isomer.