1268161-57-4

Basic information

• Product Name: S-(5-(3-nitrophenyl)-4-amino-1,2,4-triazole-3-yl) naphthalene-1-carbothioate
• Synonyms: S-(5-(3-nitrophenyl)-4-amino-1,2,4-triazole-3-yl) naphthalene-1-carbothioate
• CAS NO: 1268161-57-4
• Molecular Weight: 391.41
• Mol File: 1268161-57-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-(5-(3-nitrophenyl)-4-amino-1,2,4-triazole-3-yl) naphthalene-1-carbothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(5-(3-nitrophenyl)-4-amino-1,2,4-triazole-3-yl) naphthalene-1-carbothioate(1268161-57-4)
• EPA Substance Registry System: S-(5-(3-nitrophenyl)-4-amino-1,2,4-triazole-3-yl) naphthalene-1-carbothioate(1268161-57-4)

Safety Data

• Hazardous Substances Data: 1268161-57-4(Hazardous Substances Data)

Upstream product

• 121-92-6 3-nitrobenzoic acid 
• 618-94-0 3-nitrobenzoic acid hydrazide 
• 41421-07-2 5-(3-nitrophenyl)-1,3,4-oxadiazole-2-thiol 
• 618-95-1 methyl 3-nitrobenzoate 

Relevant articles and documents

Synthesis, characterization and antifungal evaluation of 5-substituted-4-amino-1,2,4-triazole-3-thioesters

A series of 5-substituted-4-amino-1,2,4-triazole-3-thioesters was synthesized by converting variously substituted organic acids successively into the corresponding esters, hydrazides, 5-substituted-1,3,4-oxadiazole-2-thiols, 5-substituted-1,2,4-triazole-2-thiols and 5-substituted-1,3,4-oxadiazole-2- thioesters. Finally the target compounds were obtained by refluxing 5-substituted-1,3,4-oxadiazole-2-thioesters in the presence of hydrazine hydrate and absolute alcohol. The structures of the synthesized compounds were established by physicochemical and spectroscopic methods. The synthesized compounds were evaluated for their in vitro antifungal activity. Some of the evaluated compounds possessed significant antifungal activity as compared to a terbinafine standard.