1268161-74-5

Upstream product

• 1309113-13-0 (E)-6-{[(4-methoxybenzyl)oxy]methyl}-4,4-dimethylhepta-2,6-dien-1-ol 
• 1309113-12-9 (E)-ethyl 6-{[(4-methoxybenzyl)oxy]methyl}-4,4-dimethylhepta-2,6-dienoate 
• 1309113-11-8 4-{[(4-methoxybenzyl)oxy]methyl}-2,2-dimethylpent-4-enal 
• 1531627-44-7 C₃₉H₅₂O₇ 
• 1531627-42-5 C₃₉H₅₄O₇ 
• 1531627-40-3 C₃₉H₅₀O₇ 
• 1531627-38-9 C₄₂H₅₄O₇ 
• 1309113-10-7 4-{[(4-methoxybenzyl)oxy]methyl}-2,2-dimethylpent-4-en-1-ol 
• 1531627-33-4 C₂₀H₂₇IO₄ 
• 1401338-50-8 C₁₈H₂₆O₄ 
• 1401338-49-5 C₂₄H₄₀O₄Si 
• 1401338-48-4 (2E,4E,7R,8R,9S)-ethyl 11-(tert-butyldimethylsilyl)-7,9-dihydroxy-4,8-dimethylundeca-2,4-dien-10-ynoate 
• 1309113-09-4 methyl 4-{[(4-methoxybenzyl)oxy]methyl}-2,2-dimethylpent-4-enoate 
• 1531626-73-9 (1R,3aR,4R,5S,7aR)-5-ethynyl-4-[(R)-hydroxy(4-hydroxyphenyl)methyl]-1,3,3,6-tetramethyl-2,3,3a,4,5,7a-hexahydro-1H-inden-1-ol 

Relevant academic research and scientific papers

Total synthesis of the antibiotic Elansolid B1

The antibiotic elansolid B1 was prepared by a convergent strategy that relied on a highly diastereoselective, biomimetic intramolecular Diels-Alder cycloaddition (IMDA) that furnished the tetrahydroindane unit. Other key features are a double Sonogashira cross-coupling and a substratecontrolled Yamamoto aldol reaction.

Elansolid A, a Unique Macrolide Antibiotic from Chitinophaga sancti Isolated as Two Stable Atropisomers

Inflexibility: Elansolid-A was isolated from Chitinophaga sancti (Flexibacter sancti ) as the two separable isomers A1 and A2 (1 and 1*, respectively). Molecular modeling revealed that they are stable atropisomers which are "frozen" by 14 inflexible bonds