126824-24-6

Basic information

• Product Name: BAPTA, TETRASODIUM SALT
• Synonyms: BAPTA, TETRASODIUM SALT;1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N,N-TE TRAACETIC ACID SOD.;BAPTA TETRASODIUM SALT HYDRATE, 98+%;1,2-BIS-(2-AMINOPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID TETRASODIUM;beta,Tetrasodium salt;1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N'',N''-TETRAACETIC ACID TETRASODIUM SALT HYDRATE;BAPTA-Na4, Tetrasodium 1,2-bis(2-aminophenoxy)ethane-N,N,Nμ,Nμ-tetraacetate;1,2-Bis(2-aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid tetrasodium salt,95%
• CAS NO: 126824-24-6
• Molecular Formula: C22H20N2Na4O10
• Molecular Weight: 564.36
• Mol File: 126824-24-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 766.6 °C at 760 mmHg
• Flash Point: 417.4 °C
• Appearance: beige powder
• Storage Temp.: −20°C
• Solubility: H2O: 10 mg/mL, clear, faintly yellow
• Water Solubility: Soluble in water.
• BRN: 8818619
• CAS DataBase Reference: BAPTA, TETRASODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: BAPTA, TETRASODIUM SALT(126824-24-6)
• EPA Substance Registry System: BAPTA, TETRASODIUM SALT(126824-24-6)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 126824-24-6(Hazardous Substances Data)

Usage

Chemical Properties

beige powder

Uses

Different sources of media describe the Uses of 126824-24-6 differently. You can refer to the following data:
1. Suitable as Ca2+-indicator (fluorescence suppressed by Ca2+). Chelator with a greater selectivity for calcium compared to magnesium.
2. BAPTA, Tetrasodium Salt is a selective calcium chelator with 105-fold greater affinity for Ca2+ than for Mg2+. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research.

General Description

Ca2+-chelator exhibiting a 105-fold greater affinity for Ca2+ (110 nM) than for Mg2+. After BAPTA complexes with Ca2+, the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca2+ levels, especially transient phenomena, because of its insensitivity to pH. Has been used for the measurement and control of Ca2+ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+. Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.