126827-47-2Relevant academic research and scientific papers
IMINE-ENAMINE TAUTOMERISM IN DIHYDROAZOLOPYRIMIDINES. 2. SYNTHESIS AND TAUTOMERISM OF 1,4(3,4)-DIHYDROPYRIMIDOBENZIMIDAZOLES
Desenko, S. M.,Orlov, V. D.,Lipson, V. V.,Estrada, Kh.
, p. 976 - 980 (2007/10/02)
Cyclocondensation of 2-aminobenzimidazole with unsaturated ketones or the hydrochlorides of Mannich bases has yielded aromatic substituted 1,4(3,4)-dihydropyrimidobenzimidazoles.The dependence of the tautomer composition of the products on steric factors and on the electronic character of the substituents introduced has been studied.
CYCLOCONDENSATIONS OF CHALCONES WITH 2-AMINO- AND 1,2-DIAMINOBENZIMIDAZOLES
Desenko, S. M.,Orlov, V. D.
, p. 894 - 898 (2007/10/02)
2,4-Diaryl-1,4-dihydropyrimidobenzimidazoles were obtained by the reaction of 2-aminobenzimidazole with chalcones, and their heteroaromatization was accomplished.The condensation of 1,2-diaminobenzimidazole with unsymmetrically substituted chalcones, which leads to substituted pyrimidobenzimidazoles, was studied.The specificity of this reaction was ascertained by means of alternative synthesis.
