126835-49-2Relevant academic research and scientific papers
Carbonyl Oxide Chemistry. Part 3. Regioselectivity of the First Cycloaddition of Carbonyl Oxides to Phenyl Isocyanate: One-pot Synthesis of 1,2,4-Dioxazolidin-3-ones
Iesce, M. Rosaria,Cermola, Flavio,Giordano, Federico,Scarpati, Rachele,Graziano, M. Liliana
, p. 3295 - 3298 (2007/10/02)
Carbonyl oxides 3 react with phenyl isocyanate to give the 1,2,4-dioxazolidin-3-ones 4, providing a potentially useful synthesis of a heterocyclic system which is structurally related to several biologically active products.The crystal structure of the di
Carbonyl Oxide Chemistry. Part 2. Substituent and Solvent Effects on the Chemical Behaviour of Carbonyl Oxides
Iesce, M. Rosaria,Cermola, Flavio,Graziano, M. Liliana,Scarpati, Rachele
, p. 147 - 152 (2007/10/02)
Comparison of the behaviour in polar and apolar solvents at various concentrations of the monoaryl carbonyl oxides 1 bearing an electron-withdrawing or an electron-donating group, respectively, on the aryl substituent is reported.The results are consistent with the conversion pathways reported in Scheme 1 and show that the electron-donating group increases the intramolecular oxygen-transfer potential of the system.It is also proposed that under some experimental conditions the carbonyl oxides so substituted mainly isomerize into dioxiranes 11.
