1268476-19-2Relevant academic research and scientific papers
Catalytic asymmetric carbon-carbon bond forming reactions catalyzed by tetrahydroisoquinoline (TIQ) N,N′-dioxide ligands
Cele, Zamani E.D.,Sosibo, Sphelele C.,Andersson, Pher G.,Kruger, Hendrik G.,Maguire, Glenn E.M.,Govender, Thavendran
, p. 191 - 195 (2013)
The use of TIQ-N,N′-dioxide ligands in asymmetric C-C bond forming reactions is described. In the Michael addition of cyclohexane-1,3-dione and malonates to β,γ-unsaturated α-ketoesters, excellent yields (up to 93%) and moderate to good enantioselectiviti
Highly Enantioselective Michael Addition of Cyclic Diketones to β,γ-Unsaturated α-Keto Esters Catalyzed by Squaramide Organocatalyst
Chen, Xiao-Pei,Li, Ai-Qin,Lv, Quan-Jian,Ma, Zhi-Wei,Tao, Jing-Chao,Wang, Chuan-Chuan
, (2022/01/27)
A new tertiary amine-squaramide organocatalyst has been developed and applied to the asymmetric Michael addition of cyclic diketones to β,γ-unsaturated α-keto esters. The catalyst system performed well with a low catalyst loading of 1 mol% under mild reac
Asymmetric Michael addition reactions catalyzed by a novel upper-rim functionalized calix[4]squaramide organocatalyst
Yang, Ke,Ma, Zhiyan,Tong, Hong-Xiao,Sun, Xiao-Qiang,Hu, Xiao-Yu,Li, Zheng-Yi
supporting information, p. 3259 - 3262 (2020/03/19)
A novel upper-rim functionalized calix[4]squaramide organocatalyst bearing bis-squaramide and cyclohexanediamine scaffolds was designed and prepared to catalyse a serial of asymmetric Michael addition of 1,3-dicarbonyl compounds to α,β-unsaturated carbony
Calix[4]squaramide cyclohexanediamine derivative and method for catalyzing asymmetric Michael addition and acetalization tandem reaction by using derivative
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Paragraph 0048-0054, (2019/10/10)
The invention belongs to the technical field of catalytic organic synthesis, and specifically relates to a calix[4]squaramide cyclohexanediamine derivative and a method for catalyzing an asymmetric Michael addition and acetalization tandem reaction by usi
Highly enantioselective conjugate addition of cyclic diketones to β,γ-unsaturated α-Ketoesters catalyzed by an N,N′-dioxide-Cu(OTf)2 complex
Dong, Zhenhua,Feng, Juhua,Fu, Xuan,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information; scheme or table, p. 1118 - 1121 (2011/03/21)
Copper-catalyzed conjugate addition: A highly enantioselective conjugate addition of cyclic diketones to β,γ-unsaturated α-ketoesters was achieved by using a two-carbon-linked N,N′-dioxide-Cu(OTf)2 complex. Excellent yields (up to 99%) and enan
