1268488-70-5

Basic information

• Product Name: Bis-PEG10-acid
• Synonyms: Bis-PEG10-acid;Bis-PEG25-acid;α,ω-dipropionic acid octaethylene glycol;COOH-PEG8-COOH;HOOCCH2CH2O-PEG8-CH2CH2COOH;HOOC-PEG8-COOH;Bis-PEGn-CH2CH2COOH (n=9,25)
• CAS NO: 1268488-70-5
• Molecular Formula: C22H42O13
• Molecular Weight: 514.56108
• Mol File: 1268488-70-5.mol

Chemical Properties

• Boiling Point: 630.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.174±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.97±0.10(Predicted)
• CAS DataBase Reference: Bis-PEG10-acid(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-PEG10-acid(1268488-70-5)
• EPA Substance Registry System: Bis-PEG10-acid(1268488-70-5)

Safety Data

• Hazardous Substances Data: 1268488-70-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Bis-PEG10-acid is used as a molecular linker for the conjugation of therapeutic agents, such as drugs or proteins, to improve their solubility, stability, and bioavailability. The hydrophilic PEG spacer reduces the immunogenicity and proteolytic degradation of the conjugated molecules, potentially enhancing their pharmacokinetic properties and therapeutic efficacy.
Used in Drug Delivery Systems:
In the field of drug delivery, Bis-PEG10-acid serves as a versatile component for the development of targeted drug carriers. The PEG linker can be functionalized with targeting ligands, allowing for the specific delivery of therapeutic agents to diseased cells or tissues. This targeted approach minimizes side effects and increases the overall effectiveness of the treatment.
Used in Diagnostics:
Bis-PEG10-acid can be utilized in the creation of imaging agents, where it can help improve the solubility and circulation time of diagnostic molecules in the body. The PEGylation of imaging agents can lead to enhanced contrast and more accurate detection of diseases at an early stage.
Used in Biomaterials and Tissue Engineering:
In the realm of biomaterials and tissue engineering, Bis-PEG10-acid can be employed to functionalize scaffolds or hydrogels, providing a more biocompatible and hydrophilic environment for cell growth and tissue regeneration. The PEG linker can also be used to immobilize bioactive molecules, such as growth factors, on the surface of these materials to promote specific cellular responses.
Used in Cosmetics Industry:
Bis-PEG10-acid can be used as a component in the formulation of cosmetic products, where it can enhance the solubility and stability of active ingredients. The PEG linker can also improve the skin permeation and bioavailability of these ingredients, leading to more effective cosmetic formulations with better moisturizing, anti-aging, or protective properties.