1268519-33-0Relevant articles and documents
Rhodium-catalyzed chemo-, regio-, and enantioselective addition of 2-pyridones to terminal allenes
Li, Changkun,K?hny, Matthias,Breit, Bernhard
, p. 13780 - 13784 (2014)
A rhodium-catalyzed chemo-, regio-, and enantio-selective addition of 2-pyridones to terminal allenes to give branched N-allyl 2-pyridones is reported. Preliminary mechanistic studies support the hypothesis that the reaction was initiated from the more acidic 2-hydroxypyridine form, and the initial kinetic O-allylation product was finally converted into the thermodynamically more stable N-allyl 2-pyridones.