126865-18-7

Upstream product

• 620-80-4 ethyl 2-benzylidene acetoacetate 
• 535-15-9 ethyl 1,1-dichloroacetate 
• 126865-17-6 ethyl 2-acetyl-2-(ethoxycarbonyl)-β-phenyl-1,3-dithiolane-2-propanoate 
• 1165-06-6 Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 126865-12-1 diethyl 2-acetyl-4-oxo-3-phenylpentanedioate 

Relevant academic research and scientific papers

A novel oxidation-ring-contraction of Hantzsch 1,4-dihydropyridines to polysubstituted furans

A novel oxidation-ring-contraction reaction took place when 4-substituted Hantzsch 1,4-dihydropyridines were treated with Oxone. This reaction pattern provided a convenient method for the synthesis of polysubstituted furans.

Furan Synthesis via a 4 + 1 Ring-Building Strategy - An Approach to 1,3-Diacylfurans

The reaction of 2-acyl cycloalkenones with enolates affords 1,3-diacyl furans in good yields.

Heterocyclic ring-analogs of dihydropyridine calcium antagonists

An improved synthesis of the 1,4-dihydropyrazine derivative, 3, is described that involves the versatile 1,4-diketointermediate, 9. This intermediate was converted to several heterocyclic ring-analogs of 1,4-dihydropyridine in addition to 3 including deri