1268671-28-8Relevant articles and documents
Efficient synthesis of karrikinolide via Cu(II)-catalyzed lactonization
Matsuo, Kazumasa,Shindo, Mitsuru
, p. 971 - 975 (2011)
The efficient total synthesis of karrikinolide (KAR1), a potent plant growth regulator discovered in smoke from burning plant material, is described. 3-Hydroxy-4-pyranone, prepared from d-xylose, was subjected to a Cu(II)-catalyzed transesterification-Wittig lactonization to afford the dihydrofuropyran in good yield. Finally, radical bromination, followed by olefin formation, provided KAR1 in acceptable yield.