1268682-30-9

Upstream product

• 95-79-4 5-chloro-2-methyl-benzenamine 
• 22884-95-3 3,4-dimethylbenzonitrile 
• 1268682-32-1 N-(5-chloro-2-methyl-phenyl)-3,4-dimethyl-benzamidine 
• 1268682-31-0 1-(5-chloro-2-methyl-phenyl)-2-(3,4-dimethyl-phenyl)-4-hydroxy-4,5-dihydro-1H-imidazole-4-carboxylic acid ethyl ester 

Downstream Products

• 1268682-29-6 5-bromo-1-(5-chloro-2-methyl-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-carboxylic acid ethyl ester 
• 1268675-67-7 1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-carboxylic acid ethylamide 
• 1268675-68-8 5-[1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazol-4-yl]-tetrazole 
• 1268675-69-9 1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-nitrile 
• 1268675-70-2 1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-carboxylic acid amide 
• 1268675-71-3 1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-carboxylic acid 
• 1268675-72-4 1-(5-chloro-2-methyl-phenyl)-5-(3-chloro-phenyl)-2-(3,4-dimethyl-phenyl)-1H-imidazole-4-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS

The invention relates to tetra-substituted heteroarylic compounds of the formula (I) wherein X1, X3 and X4 are independently C or N, Y is C-H, N-H or N, wherein the total number of nitrogen atoms represented by X1/su