1268816-80-3

Usage

Uses

Used in Pharmaceutical Industry:
(2S,6S)-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester is used as a building block in organic synthesis and medicinal chemistry for its potential applications in drug discovery and development. Its unique structure and functional groups enable the creation of various pharmaceutical compounds.
Used in Organic Chemistry Research:
(2S,6S)-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester is also used in the study of organic reaction mechanisms, where its stereoisomerism and functional groups can provide insights into the behavior of similar compounds and contribute to the advancement of organic chemistry knowledge.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 13200-35-6 (2S,6R)-2,6-dimethylpiperidin-4-one 

Relevant academic research and scientific papers

METHOD OF INHIBITING C-KIT KINASE

A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.

INHIBITORS OF C-FMS KINASE

The invention is directed to compounds of Formula (I): wherein A, X, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, colon cancer, stomach cancer, hairy cell leukemia and non-small lung carcinoma; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, Paget's disease, and other diseases in which bone resorption mediates morbidity including arthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of Formula (I), are also provided.