1268853-79-7Relevant academic research and scientific papers
ENANTIOSELECTIVE CYCLOPROPENATION OF ALKYNES
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Paragraph 0084; 0104; 0105, (2013/03/26)
The cobalt(II) complex of new D2-symmetric chiral porphyrin 3,5-DiMes-ChenPhyrin, [Co(P2)], has been shown to be a highly effective chiral metalloradical catalyst for enantioselective cyclopropenation of alkynes with acceptor/acceptor-substituted diazo re
Enantioselective cyclopropenation of alkynes with acceptor/acceptor- substituted diazo reagents via Co(II)-based metalloradical catalysis
Cui, Xin,Xu, Xue,Lu, Hongjian,Zhu, Shifa,Wojtas, Lukasz,Zhang, X. Peter
supporting information; experimental part, p. 3304 - 3307 (2011/04/24)
The cobalt(II) complex of a new D2-symmetric chiral porphyrin 3,5-diMes-ChenPhyrin, [Co(P2)], has been shown to be a highly effective chiral metalloradical catalyst for enantioselective cyclopropenation of alkynes with acceptor/acceptor-substituted diazo reagents, such as α- cyanodiazoacetamides and α-cyanodiazoacetates. The [Co(P2)]-mediated metalloradical cyclopropenation is suitable to a wide range of terminal aromatic and related conjugated alkynes with varied steric and electronic properties, providing the corresponding trisubstituted cyclopropenes in high yields with excellent enantiocontrol of the all-carbon quaternary stereogenic centers. In addition to mild reaction conditions, the Co(II)-based metalloradical catalysis for cyclopropenation features a high degree of functional group tolerance.
