126893-92-3

Upstream product

• 13138-21-1 diazoacetonitrile 
• 2493-02-9 4-bromophenyl isocyanate 
• 287474-44-6 N-(4-bromo-phenyl)-2-cyano-2-diazo-acetamide 

Relevant academic research and scientific papers

Heterocyclization of compounds containing diazo and cyano groups. 6. Theoretical and experimental investigations of cyclization of 2-cyano-2-diazoacetamides to 5-hydroxy-1,2,3-triazole-4-carbonitriles

A series of N-alkyl- and N-aryl-2-cyano-2-diazoacetamides was synthesized by the reaction of 2-amino-2-cyanoacetamides with sodium nitrite in hydrochloric acid. The mechanism of their heteroelectrocyclization to 5-hydroxy-1,2,3-triazoles was investigated

ELECTROPHILIC SUBSTITUTION OF HYDROGEN IN DIAZOACETONITRILE

2-Carbonyl-substituted diazoacetonitriles were obtained by the reaction of diazoacetonitile with carboxylic acid chlorides and isocyanates.The acyl derivatives of diazoacetonitriles were identified in the form of the corresponding triphenylphosphazines.The carbamoylation products undergo cyclization to 1-substituted 4-cyano-5-hydroxy-1,2,3-triazoles in the course of the reaction.