126912-60-5Relevant academic research and scientific papers
Asymmetric Synthesis of Alkyl Fluorides: Hydrogenation of Fluorinated Olefins
Ponra, Sudipta,Yang, Jianping,Kerdphon, Sutthichat,Andersson, Pher G.
, p. 9282 - 9287 (2019/05/28)
The development of new general methods for the synthesis of chiral fluorine-containing molecules is important for several scientific disciplines. We herein disclose a straightforward method for the preparation of chiral organofluorine molecules that is ba
A facile and mild approach for stereoselective synthesis of α-fluoro-α,β-unsaturated esters from α-fluoro-β-keto esters via deacylation
Qian, Jinlong,Yi, Wenbin,Lv, Meifang,Cai, Chun
, p. 127 - 132 (2015/02/02)
The highly stereoselective olefination reaction of α-fluoro-β-keto esters for the synthesis of α-fluoro-α,β-unsaturated esters has been developed. The olefination combines nucleophilic addition, intramolecular nucleophilic addition, and elimination in one step, as well as provides a facile synthetic approach to α-fluoro-α,β-unsaturated esters which are important units in many biologically active compounds and useful precursors in a variety of functional-group transformations.
FLUORINE-CONTAINING CHALCONES. III. REARRANGEMENT OF 1,3-DIARYL-1,2-DIFLUORO-1-PROPEN-3-OLS TO Α-FLUOROCHALCONES
Yarmolenko, S. N.,Fialkov, Yu. A.,Yagupol'skii, L. M.
, p. 1767 - 1774 (2007/10/02)
1,3-Diaryl-1,2-difluoro-1-propen-3-ols were synthesized by the reaction of 4-substituted α,β-difluorostyryllithium and benzaldehyde.When heated or in an acidic medium they readily rearrange with the elimination of HF to the corresponding 4- and 4'-substit
