1269183-36-9Relevant academic research and scientific papers
Synthesis of 6-trifluoromethylindolo[1,2-c]quinazolines and related heterocycles using N-(2-iodophenyl)trifluoroacetimidoyl chlorides as starting material via C-H bond functionalization
Zhu, Jiangtao,Xie, Haibo,Chen, Zixian,Li, Shan,Wu, Yongming
scheme or table, p. 1512 - 1514 (2011/04/15)
A mild, two-step reaction for the synthesis of 6-trifluoromethylindolo[1,2- c]quinazolines from readily available indoles and N-(2-iodophenyl) trifluoroacetimidoyl chlorides via addition-elimination/arylation is described. An array of aza-fused trifluoromethylated heterocycles can be easily assembled via Friedel-Crafts reaction/C-H bond activation by this methodology.
