126924-19-4

Upstream product

• 20698-91-3 (R)-methyl mandelate 
• 611-71-2 (R)-Mandelic Acid 
• 10606-72-1 (R)-mandelic acid ethyl ester 

Downstream Products

• 121129-39-3 (1S,4R)-3-<(2R)-2-hydroxy-2-phenylacetyl>-2-oxa-3-azabicyclo<2.2.2>oct-5-ene 
• 121129-39-3 (1R,4S)-3-<(2R)-2-hydroxy-2-phenylacetyl>-2-oxa-3-azabicyclo<2.2.2>oct-5-ene 
• 1310055-77-6 (2R)-2-hydroxy-N-[(1R,4R,5R)-4-hydroxy-5-phthalimidocyclohex-2-en-1-yl]-2-phenylacetamide 
• 1310055-79-8 (2R)-2-hydroxy-N-[(1S,4R,5R)-4-hydroxy-5-phthalimidocyclohex-1-yl]-2-phenylacetamide 
• 121129-35-9 2-Mandeloyl-3,6-dihydro-3,6-methano-2H-1,2-oxazine 
• 134235-14-6 (1R,2R,3S,4S,5S)-1-(methylthio)-2,3,4-triacetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopentane 
• 134153-74-5 (1R,2R,3R,4R,5S)-1-(methylthio)-2,3,4-triacetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopentane 
• 134153-73-4 (1R,2R,5S)-1-(methylthio)-2-acetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopent-3-ene 
• 134153-75-6 (1R,2R,5S)-1-(methylthio)-2-hydroxy-5-(N-((R)-hydroxyphenylacetyl)amino)cyclopent-3-ene 
• 134153-72-3 (1R,4S,7R)-7-(methylthio)-3-(oxophenylacetyl)-2-oxa-3-azabicyclo<2.2.1>hept-5-ene 
• 172476-78-7 (R)-2,N-Dihydroxy-N-((1R,2S)-2-hydroxy-cyclopent-3-enyl)-2-phenyl-acetamide 
• 172476-76-5 1-(1S,4R)-2-Oxa-3-aza-bicyclo[2.2.1]hept-5-en-3-yl-2-phenyl-ethane-1,2-dione 

Relevant academic research and scientific papers

Preparation method (1R,3S)-3- amino cyclopentanol chiral acid salt (by machine translation)

The invention discloses a preparation method (1R,3S) - 3 - of, amino cyclopentanol chiral acid salt, wherein the (1R,3S) - 3 - amino cyclopentanol chiral acid salt is a compound, of formula I and comprises a step e or step d-e or step c-d-e or step a-b-c-

A (1 R, 3 S) -3 - amino-cyclopentanol hydrochloride preparation method (by machine translation)

The invention discloses a (1 R, 3 S) - 3 - amino-cyclopentanol hydrochloride of the preparation method, the method using chiral carboxylic acid with hydroxylamine to form the amide as chiral source, in copper catalyzed oxidation in the reaction system to rapidly obtain a chiral Diels - alder reaction product, after passes through the reduction reaction and alkaline deprotection reaction, and acidified after reaction to obtain the target product. Chiral inducing reagent chiral carboxylic acid by simple acidification, extraction processing can be reclaimed and reused. This kind of (1 R, 3 S) - 3 - amino-cyclopentanol hydrochloride preparation method has high operation safety and high selectivity, raw materials are easy, and the cost is low, the reaction time is short and simple process flow and the like. (by machine translation)

Mandelohydroxamic acid as ligand for copper(II) 15-metallacrown-5 lanthanide(III) and copper(II) 15-metallacrown-5 uranyl complexes

The formation of pentanuclear copper(II) complexes with the mandelohydroxamic ligand was studied in solution by electrospray ionization mass spectrometry (ESI-MS), absorption spectrophotometry, circular dichroism and 1H NMR spectroscopy. The pr

Asymmetric Induction in the Diels-Alder Reactions of α-Hydroxy Acyl Nitrones

The hydroxamic acids 7, derived from a series of α-hydroxy acids 5, have been oxidised with periodate to form transient, chiral acyl nitroso compounds 8, which were trapped in situ with cyclopentadiene and cyclohex-1,3-diene to give mixtures of diastereoi

Asymmetric Diels-Alder Cycloadditions with Chiral Carbamoyl Dienophiles

Chiral acylnitroso dienophiles 14, which were obtained from L-proline and from D-mandelic acid, reacted with cyclohexa-1,3-diene to give the expected diastereoisomers 15 and 16 (Scheme 2 and Table 1).The d.e. values for these Diels-Alder reactions were moderate; they are related to the molecular stiffness of the dienophiles.The absolute configuration of the major cycloadducts was interpreted in terms of HOMO/LUMO interactions, the approach being 'endo' and the acylnitroso dienophiles reacting from their s-cis-conformation.