1269261-55-3

Upstream product

• 895578-42-4 N-(2-(chloromethyl)-4-chlorophenyl)-4-methylbenzenesulfonamide 
• 2622-05-1 allylmagnesium bromide 
• 675578-47-9 N-(4-chloro-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 37585-25-4 2-amino-5-chlorobenzyl alcohol 

Downstream Products

• 1269261-72-4 2-(bromomethyl)-6-chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydroquinoline 
• 1421826-93-8 (6-chloro-1-tosyl-1,2,3,4-tetrahydroquinolin-2-yl)-methyl acetate 

Relevant academic research and scientific papers

Palladium(II)-catalyzed aerobic intramolecular allylic C[sbnd]H activation for the synthesis of indolines

A method for the preparation of indolines via palladium-catalyzed aerobic intramolecular allylic C[sbnd]H activation was developed. Oxygen was successfully used as oxidant with catalytic amount of 1,4-benzoquinone. 16 examples were reported, the majority of substrates gave moderate to good yields.

Pd(II)-catalyzed oxidative cyclization reaction for the preparation of 2-substituted 1,2,3,4-tetrahydroquinolines with halide functionality

The first Pd(II)-catalyzed oxidative cyclization reaction was developed for preparation of 2-substituted 1,2,3,4-tetrahydroquinolines from olefinic tosylamides. Under the optimized conditions, up to 86% yield was obtained. This reaction provides direct an