1269293-80-2

Usage

Uses

Used in Organic Synthesis:
5-Bromo-1-methyl-1H-pyrazole-4-carbonitrile is utilized as a reagent in organic synthesis for the preparation of a range of pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with potential therapeutic and pesticidal properties.
Used in Drug Discovery and Development:
As a valuable intermediate, 5-Bromo-1-methyl-1H-pyrazole-4-carbonitrile is employed in drug discovery and development processes. Its potential biological activities, such as enzyme inhibition, make it a promising candidate for the creation of new drugs targeting specific biological pathways.
Used in Enzyme Inhibition Studies:
5-Bromo-1-methyl-1H-pyrazole-4-carbonitrile has been studied for its potential as an inhibitor of certain enzymes. This application is crucial in the development of drugs that can modulate enzyme activity, thereby affecting various biological processes and treating diseases.
Used in the Synthesis of Biologically Active Molecules:
5-Bromo-1-methyl-1H-pyrazole-4-carbonitrile also serves as a building block for the synthesis of biologically active molecules. Its structural features make it a key component in the creation of new molecules with potential applications in medicine and agriculture, contributing to the advancement of novel therapeutic agents and crop protection products.

Upstream product

• 5334-41-8 5-amino-4-cyano-1-methylpyrazole 

Relevant academic research and scientific papers

PROCESS OF PREPARATION OF AZIMSULFURON

The present disclosure provides process for preparation of azimsulfuron or its salts, isomers, and other derivatives thereof. The process involves treating a compound of formula I, with aqueous acetic acid or formic acid and chlorine gas or sodium hypochlorite in presence of hydrochloric acid in chlorinated solvents such as dichloromethane, 1,2-dichloroethane or with aqueous acetic acid and N-chlorosuccinimide or hydrogen peroxide in presence of hydrochloric acid in aqueous cyclic ether such as tetrahydrofuran, 1,4-dioxane to obtain 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonyl chloride; converting the sulfonyl chloride to a sulfonamide and treating the sulfonamide with a phenyl(4,6-dimethoxypyrimidin-2-yl) carbamate to obtain azimsulfuron or its salts, isomers, and other derivatives thereof.

PROCESS OF PREPARATION OF AZIMSULFURON

The present disclosure provides process for preparation of azimsulfuron or its salts, isomers, and other derivatives thereof. The process involves treating a compound of formula I, (Formula I should be inserted here.) with aqueous acetic acid or formic acid and chlorine gas or sodium hypochlorite in presence of hydrochloric acid in chlorinated solvents such as dichloromethane, 1,2-dichloroethane or with aqueous acetic acid and N-chlorosuccinimide or hydrogen peroxide in presence of hydrochloric acid in aqueous cyclic ether such as tetrahydrofuran, 1,4-dioxane to obtain 1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonyl chloride; converting the sulfonyl chloride to a sulfonamide and treating the sulfonamide with a phenyl(4,6-dimethoxypyrimidin-2-yl) carbamate to obtain azimsulfuron or its salts, isomers, and other derivatives thereof.

SUBSTITUTED TETRAZOLE COMPOUNDS AND PROCESS THEREOF

The present disclosure provides a compound of formula I, its derivatives, salts, stereo-isomers, or regio-isomers thereof, useful as intermediates in preparation of sulfonamide or sulfonyl urea growth regulators or herbicides. Formula I The present disclosure further provides a process for preparing compound of formula I, its derivatives, salts, stereo-isomers, or regio-isomers thereof.

SUBSTITUTUED PYRAZOLE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF.

The present disclosure provides a compound of formula I, its derivatives, salts, stereo-isomers, or regio-isomers thereof, useful as intermediates in preparation of sulfonamide or sulfonyl urea growth regulators or herbicides. Formula I The present disclosure further provides a process for preparing compound of formula I, its derivatives, salts, stereo-isomers, or regio-isomers thereof.