126931-29-1

Basic information

• Product Name: 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol
• Synonyms: 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol;4-((tert-ButyldiMethylsilyl)oxy)cyclohexanol
• CAS NO: 126931-29-1
• Molecular Formula: C₁₂H₂₆O₂Si
• Molecular Weight: 230.421
• EINECS: 604-604-1
• Mol File: 126931-29-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 265.7±33.0 °C(Predicted)
• Appearance: /
• Density: 0.92±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 14.98±0.40(Predicted)
• CAS DataBase Reference: 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol(126931-29-1)
• EPA Substance Registry System: 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol(126931-29-1)

Safety Data

• Hazardous Substances Data: 126931-29-1(Hazardous Substances Data)

Usage

General Description

4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol is a chemical compound with a cyclohexanol core and a tert-butyl-dimethyl-silanyloxy substituent. The tert-butyl group is a branch of three carbon atoms, while the dimethyl-silanyloxy group is a silicon-containing functional group. 4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexanol is often used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It can serve as a protecting group for alcohols, enabling selective reactions in organic synthesis. Its unique structure and functional groups allow for various chemical reactions and applications in the field of organic chemistry.

Upstream product

• 1036648-31-3 4-(tert-butyldimethylsilyloxy)cyclohexyl 4-methylbenzoate 
• 55145-45-4 4-(tert-butyldimethylsilyloxy)cyclohexanone 
• 556-48-9 1,4-Cyclohexanediol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1028716-12-2 5-{[3-fluoro-2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-3-{4-[(4-hydroxycyclohexyl)oxy]phenyl}-2-methyl-6-propylpyrimidin-4(3H)-one 
• 18068-06-9 4-methoxycyclohexan-1-ol 
• 1356016-24-4 tert-butyl-[4-(4-chloro-2-nitro-phenoxy)-cyclohexyloxy]-dimethyl-silane 
• 1356016-25-5 2-[4-(tert-butyl-dimethyl-silanyloxy)-cyclohexyloxy]-5-chloro-phenylamine 
• 1262219-78-2 4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyldiphenylphosphinate 
• 67124-67-8 1-(tert-butyldimethylsiloxy)cyclohexane 
• 1246655-00-4 ethyl 5-(tert-butyldimethylsilyloxy)-1-(iodomethyl)-2-oxocyclohexanecarboxylate 

Relevant articles and documents

BICYCLIC FUSED PYRIDINE COMPOUNDS AS INHIBITORS OF TAM KINASES

Provided herein are compounds of the Formula (I): and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein Ring A, X1, X2, X3, R1, R2 and R3 are as defined herein

NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES

Disclosed herein are 5 or 8-substituted imidazo[l,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[l,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8- substituted imidazo[l,5-a]pyridines that can be useful for inhibiting indoleamine 2,3- dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.