1269409-82-6Relevant articles and documents
Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues
Diez-Torrubia, Alberto,Balzarini, Jan,Andrei, Graciela,Snoeck, Robert,De Meester, Ingrid,Camarasa, María-José,Velázquez, Sonsoles
, p. 1927 - 1942 (2011/05/17)
We present the first report of the application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to hydroxy-containing drug derivatives. In particular, we applied this strategy to the highly lipophilic antiviral drug family of bicyclic fu